No.27 May 2023

Health control and pathology

Editorial

Prof. Evgeny Ilyich Mayevsky, DM

Head of the Laboratory of Energetics of Biological Systems at the Institute of Theoretical and Experimental Biophysics at the Russian Academy of Sciences.

Original research

Effect made by the growth of multiple primary malignant tumors on the hypothalamic-pituitary-gonadal axis in BALB/c Nude mice of both sexes

Oleg I. Kit, Elena M. Frantsiyants, Valeriya A. Bandovkina, Irina V. Kaplieva, Alla I. Shikhlyarova, Ekaterina I. Surikova, Irina V. Neskubina, Natalia D. Cheryarina, Yulia A. Pogorelova, Lidia K. Trepitaki, Inga M. Kotieva, Lyudmila Y. Rozenko, Marina A. Arzamastseva, Elena I. Agarkova, Marina M. Sergeeva

Hypothalamic-pituitary-gonadal axis Sex steroids Melanoma Lewis carcinoma BALB/c Nude mice

Original research

Role of hypothalamic-pituitary-gonadal regulatory axis in growth of melanoma В16/F10 in С57/BL6 mice

Oleg I. Kit, Valeriya A. Bandovkina, Elena M. Frantsiyants, Irina V. Kaplieva, Natalia D. Cheryarina, Viktoria V. Pozdnyakova, Lidia K. Trepitaki, Yulia A. Pogorelova, Polina S. Kachesova, Marina A. Gusareva, Ekaterina S. Bosenko, Lyudmila P. Kuchkina, Natalia S. Saforiyn, Marina S. Kuznetsova

B16/F10 melanoma Hypothalamic-pituitary-gonadal axis Regulatory peptides Steroid hormones Receptors

Original research

Trigeminy electrocardiogram spectral characteristics study

Proskurin S.G.

Digital ECG processing Allorhythmia Trigeminy Spectral analysis ECG harmonic’s characteristics

Original research

Analysis of the infectious morbidity in the children's population in the city of Krasnodar

Justina Oluwatoyin Aleksovna Oguntimehin, Aizanat M. Jalalova, Kristina M. Krasnikova, Olga V. Alekseenko, Ulyana Y. Senkovich, Sabina R. Zeynalova

Children’s age Infectious diseases Infectious agents Morbidity Acute respiratory infections SARS-CoV-2 Vaccination

Original research

Features of perioperative management of pediatric patients with congenital heart defects

Ronay B. Sheker, Ruslan R. Nurgalin, Galina M. Yakovleva, Nataliya A. Zholobova, Frederika N. Nikonova, Vasiliy A. Kozhushkov, Ivan A. Kozhushkov, Nataliia E. Chebotar, Izobella A. Mussova, Vera I. Bychkova

Congenital heart defects Children's patients Surgical treatment Individual approaches.

Original research

Development of the basilar artery system in the human embryonic period

Alexey V. Gorbunov, Maria G. Kalugina

Basilar artery Embryo Pre-fetus

Original research

Significance of coping strategies on the outcome of surgical treatment of patients with prosoplegia

Dmitriy A. Gulyaev, Tatiana A. Kaurova, Ivan A. Kurnosov, Kseniya A. Chizhova, Igor V. Yakovenko

Facial nerve Prosoplegia Surgical treatment Coping strategies Neuropsychological status

Original research

To study about the relation between oxygen delivery and hemodynamics during cardiopulmonary bypass

Dr Ashwanth P Reddy, R. Sunitha, Dr. Periyasamy Thangavel, Dr. J. Ramkumar, S. George Miller

Heart Disease Oxygen Patients Surgery

Original research

Age-related risk factors affecting the population morbidity

Kristina A. Sytdykova, Yana V. Kazantseva, Ariana M. Sinanyan, Maria N. Dulkina, Gleb O. Fatenkov, Marina A. Fatenkova

Age Risk factors Population morbidity Influence of factors

Original research

Disorders in connections of the hypothalamic-pituitary-gonadal axis in rats with Guerin's carcinoma against the background of induced hypothyroidism

Oleg I. Kit, Valeriya A. Bandovkina, Elena M. Frantsiyants, Irina V. Kaplieva, Ekaterina I. Surikova, Irina V. Neskubina, Natalia D. Cheryarina, Yulia A. Pogorelova, Lidia K. Trepitaki, Lyudmila A. Nemashkalova, Tatyana I. Moiseenko, Alina Y. Arakelova

Hypothyroidism Guerin's carcinoma Rats Hypothalamic-pituitary-gonadal axis

Original research

Features of changes in the content of hormones of the hypothalamic-pituitary tract depending on the independent or combined variant of B16/F10 melanoma growth in mice of both sexes

Oleg I. Kit, Elena M. Frantsiyants, Valeriya A. Bandovkina, Irina V. Kaplieva, Alla I. Shikhlyarova, Ekaterina I. Surikova, Iirina V. Neskubina, Natalia D. Cheryarina, Yulia A. Pogorelova, Lidia K. Trepitaki, Inga M. Kotieva, Larisa N. Vaschenko, Yulia Y. Kozel, Anna S. Egorova

B16/F10 melanoma Hypothalamic releasing hormones Pituitary tropic hormones

Original research

Differences in the functioning of the hypothalamic-pituitary-gonadal axis of regulation in male rats at one (liver) site and two (liver and lungs) sites of metastasis of sarcoma 45 in the experiment

Oleg I. Kit, Irina V. Kaplieva, Elena M. Frantsiyants, Lidia K. Trepitaki, Valeriya A. Bandovkina, Yulia A. Pogorelova, Irina A. Goroshinskaya, Ekaterina I. Surikova, Irina V. Neskubina, Galina V. Zhukova, Alla I. Shikhlyarova, Marina A. Engibaryan, Tatiana V. Ausheva, Viktoria L. Volkova, Marina A. Gusareva, Polina S. Kachesova

Metastases Liver Hypothalamic-pituitary-gonadal axis Sex steroids Rats Males Sarcoma 45

Original research

Protein system of bacillus anthracis antigens

Aleksandr V. Tsekhomsky, Angelina S. Balchevskaya

Bacillus anthracis Anthrax Antigen Exotaxin Protein system

Original research

Problematic aspects of the use of artificial intelligence capabilities in modern medical diagnostics

Ivan S. Shipilov, Alim A. Bakaev, Abdurauf Sh. Bobokhodzhiev, Dana B. Kyagova, Rasul Kh. Chotchaev, Alina I. Muzafarova, Ilia U. Golubev, Sergei A. Pergunov

Medical diagnostics Artificial intelligence Individual diagnostic capabilities Problematic as-pects

Original research

Features of the use of regional anesthesia in the surgical correction of traumatic defects of the bones of the skull and spine reconstructive plastic surgery

Armen A. Daniliyants, Fatima R. Botasheva, Marina A. Daurova, Elizaveta S. Sibirkina, Karen L. Tohiyan, Ismailgadzhi Z. Mustafaev, Umar D. Begereev, Djamilya M. Idrisova

Regional anesthesia Surgical correction Traumatic defects of the skull bones Reconstructive plastic surgery

Original research

Endocrine emergencies: clinical manifestations, operative diagnostics and emergency medical care

Elizaveta R. Karpenko, Irina D. Gurova, Anna E. Pogodina, Anastasia N. Kompaniets, Valeria E. Bairova, Daria A. Zaichuk, Anastasia A. Egorova

Endocrinology Emergency conditions Clinical manifestations of endocrine pathologies Opera-tive diagnostics Emergency medical care

Original research

Predictors of Suboptimal Reperfusion and Short Term Mortality in Patients Presented With Acute ST-Segment Elevation Myocardial Infarction and Treated With Primary Percutaneous Coronary Intervention

Mahmoud Shawky Abdelmoneum, Osama Sanad Arafa, Osama Abd El Momen Mohamed, Mohamed Ebrahim Abd El Maksod, Hager Ibrahim Allam

Suboptimal reperfusion Primary percutaneous coronary intervention Acute ST-segment elevation myocardial infarction

Original research

Effects of cardiopulmonary bypass on liver function in patients undergoing cardiac surgery

Dr. Ashwanth P Reddy, R. Sunitha, Dr. Periyasamy Thangavel, Dr. J. Ramkumar, S. George Miller

Cardiopulmonary bypass Pre & post-operative results Liver dysfunction Hepatic failure

Original research

The problem of bleeding in the postpartum period

Tatiana E. Onbysh, Anastasia V. Malukha, Ekaterina A. Ponomareva, Ksenia V. Sitnikova

Bleeding Postpartum period Obstetrics Diagnostics Treatment Prevention

Original research

Influence by hypothyroidism on the level of sex hormones in blood and their intracrine content in the tumor in rats with Guerin's carcinoma

Oleg I. Kit, Valeriya A. Bandovkina, Elena M. Frantsiyants, Irina V. Kaplieva, Alla I. Shikhlyarova, Ekaterina I. Surikova, Irina V. Neskubina, Natalia D. Cheryarina, Yulia A. Pogorelova, Lidia K. Trepitaki, Alina Y. Arakelova, Natalia A. Maksimova, Yury A. Poryvaev, Maria G. Ilchenko

Hypothyroidism Guerin's carcinoma Estradiol Testosterone Progesterone

Original research

Changes in the functional activity of the hypothalamic-pituitary-adrenal axis in rats of both sexes with Guerin's carcinoma against the background of hypothyroidism

Oleg I. Kit, Elena M. Frantsiyants, Valeriya A. Bandovkina, Irina V. Kaplieva, Ekaterina I. Surikova, Irina V. Neskubina, Natalia D. Cheryarina, Lidia K. Trepitaki, Yulia A. Pogorelova, Irina A. Goroshinskaya, Galina V. Zhukova, Alina Y. Arakelova, Larisa N. Vaschenko, Vera A. Kovalenko, Oksana V. Bykadorova, Alena S. Kuligina

Guerin's carcinoma Tumor Hypothyroidism CT-releasing hormone ACTH Cortisol

Original research

Secondary metabolites of Schisandra chinensis in homeostasis regulator adaptogen herbal formula for preventive oncology

Olga A. Bocharova, Ilia V. Kazeev, Valeriy E. Shevchenko, Nikita S. Ionov, Olga P.Sheichenko, Evgeny V. Bocharov , Regina V. Karpova, Valerian G. Kucheryanu, Alexey A. Lagunin, Dmitry A. Filimonov, Vyacheslav S. Kosorukov, Vladimir V. Poroikov, Victor A. Tutelyan, Natalya V. Pyatigorskaya

Herbal formula MPhA Schisándra chinénsis Schizandrin and Schizantherin A adaptogen Homeostasis regulator Preventive oncology Standardization HPLC-MS/MS spectroscopy PASS PharmaExpert in silico analysis

Original research

Features of the course of Covid-19 infection in children

Ilona K. Nakhusheva, Darya O. Yurchenko, Milena M. Sviridova, Nikita K. Dzhgarkava, Mark V. Yarosh, Yulia E. Emets

COVID-19 SARS-CoV-2 ACE2 Pediatrics Multisystem inflammatory syndrome

Original research

Application of digital methods and artificial intelligence capabilities for diagnostics in obstetrics and gynecology

Elvira R. Safiullina, Ekaterina I. Rychkova, Irina V. Мayorova, Diana Kh. Khairutdinova, Anna A. Slonskaya, Anna S. Faronova, Yaroslava A. Davydova, Izobella A. Mussova

Obstetrics Gynecology Diagnostics Digital methods Artificial intelligence

Original research

Separate approaches to the provision of emergency psychological, psychiatric and psychotherapeutic assistance in emergency situations

Elizaveta S. Shevchenko, Egor A. Pivovarov, Elena V. Dmitrieva

Emergency psychological and psychiatric care Psychotherapeutic care Emergency situations

Original research

Analysis of methods for assessing threats in the field of data storage

Viktor M. Kureichik, Sergey S. Pirozhkov, Olga N. Sakharova, Konstantin V. Kamyshev, Elena N. Kamenskaya, Murat P. Deberdeev

Cybersecurity Threats Data Storage

Original research

Comparative study between sugammedex and neostigmine as a reversal agent of rocuronium for pediatric patients 2-12 years old going for surgery under general anaesthesia

Hanan Ebeid Abdou Abed, Ahmed M R Abdelaziz

Analgesics Central Nervous System Muscle Relaxants Neuromuscular Blockers Neostigmine Pediatric Patients Pain Reversal Agents Surgery Sugammadex

Original research

Features of the first-year students’ lifestyle at the faculty of medicine: an observational study

Darina A. Yahagoeva, Darina A. Zhurtova, Аksana M. Kаrdаngushevа, Ilona S. Khagabanova, Elvira K. Appaeva, Dinara R. Zherukova

Health Medical students Healthy lifestyle Physical activity Nutrition Smoking Alcohol Bad habits

Original research

Interaction between the mother and the fetus in the aspect of immunology

Tatiana E. Onbysh, Margarita V. Vilkova, Elizaveta E. Dubovik, Evgeny A. Nosov

Immune system Pregnancy Fetus Autoimmune diseases Immunodeficiencies Rh conflict Antiphospholipid syndrome Preeclampsia Immunology

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