We are pleased to offer new papers to outline breaking-through research topics in cardio- and neurophysiology
No.17 November 2020
Cardio- and neurophysiology
Electrocardiogram frequency characteristics study by processing and analysis of the signal in time domain and spectral domain
This paper presents the results of a study in which cardiac signal of the first lead of a standard digital ECG system were processed. By filtering in the time domain, the cardiogram was clarified of noise that reduced influence of spectral harmonics by 10-15%.
Digital electrocardiogramDigital ECG processingECG smoothingSpectral analysis
Chronic neurogenic pain is responsible for changes in concentrations of biogenic amines in the brain in urokinase knockout mice with melanoma В16/F10
Our aim is to study special features of actions and effects of chronic neurogenic pain on concentrations of biogenic amines in the brain in tumor-bearing urokinase knockout mice (uPA).
С57/В16 mice lineUPABrain biogenic aminesChronic neurogenic painInoculated melanoma В16/F10
The impact of multiple overlapping new generations drug-eluting stents on six-month clinical outcomes in patients with anterior STEMI treated with primary PCI
Implantation of multiple (≥ 2) overlapping stents has been associated with adverse outcomes after percutaneous coronary intervention (PCI).
ST elevation myocardial infarctionPercutaneous coronary interventionDrug-eluting stentsStent overlap
The article presents the state of the cardiovascular system of smokers with different periods of tobacco smoking.
HeartBlood pressureAtrial systoleTime of ventricular excitation
Succinic acid, being a metabolite of the Krebs cycle and the end product of anaerobic transformations in mitochondria, functions outside mitochondria and cells as a regulatory signal.
Adaptive succinate gainStabilization HIFSuccinate receptor activation
The aim hereof is to identify changes in the performance of the CNS neurons under the prolonged action of low-threshold pain factor according to indicators of the membrane potential level, parameters of the action potential and the pattern of the firing activity distribution of the neurons.
NeuronCardiomyocyteMembrane potentialFiring rateLow-intensity stimulationPain
In the study conducted by us previously, it was found that not only the energy of the discharge, but also the amplitude of current, the pulse duration and its shape have their significant influence on the efficacy of defibrillation.
Transthoracic defibrillationBiphasic pulseCurrent stabilizationCardiomyocytes repolarizationVentricular fibrillation
Influence of urokinase gene knockout on level of prekallikrein and kallikreins 1 and 14 in mice with melanoma growth against the background of pain
The aim is to study the content of prekallikrein, kallikreins 1 and 14 (KLK-1 and KLK-14) in mice under the conditions of activation and inhibition of the B16/F10 inoculated melanoma growth.
MiceUPA knockoutB16/F10 melanomaChronic neurogenic painKallikrein-kinin systemSkinTumor
Artificial neural networkECGCardiometry
Functional state of the cardiovascular system in female students with different academic performance grades
The work is devoted to the study of the functional state of the cardiovascular system in female students with different academic success.
StudentAcademic performanceHeart rateArterial pressureMinute blood volume
Estimation of the cardiovascular morbidity in the population of the Kabardino-Balkarian Republic according to the number of visits to health care offices
The aim is to evaluate the level, structure and dynamics of cardiovascular morbidity in the Kabardino-Balkarian Republic for the period from 2014 to 2019.
MorbidityCirculatory system diseasesCerebrovascular diseaseIschemic heart diseaseArterial hypertension
Anti-tumor, anti-edematous and analgesic effects of transcranial magnetic therapy in complex treatment of brain tumors of a high degree of malignancy
The results obtained in this study have demonstrated a possibility to increase the efficacy of the complex treatment of patients with brain tumors of a high degree of malignancy with the use of factors of the magnetic-wave nature, including low-intensity PMF and ELF MF, which can be integrated into the adjuvant therapy scope.
GlioblastomasElectromagnetic fieldsApoptosisNeurogenic painAnti-edematous effectCorrection of phsychosomatic and vascular disorders
Prospects for cardiovascular system telemonitoring in solving tasks in Federal National Project “Generation Seniors”
The paper presents an analysis of some promising lines of developing off-office telemonitoring. Some applications of expert systems designed on the basis of algorithms used for medical decision making are discussed herein.
TelemedicineTelemonitoringInformation technologiesOff-office monitoringExpert systemsMedical decision makingGeriatryMedical follow-up
Approaches to the gene therapeutic correction of the pathogenetic mechanisms of coronary insufficiency
The absence of neoangiogenesis in the ischemic myocardium is the reason for the widespread prevalence of cardiovascular diseases.
Coronary insufficiencyTherapeutic angiogenesisGrowth factorsGene plasmids
Methodological foundations for ensuring the stability in training athletes of various kinds of sports
A unified approach to the problems of health preservation in athletes, taking into account the options for phenotyping their health and basing on the main indicators of homeostatic potential.
Health phenotypingHomeostatic potentialReserve capabilitiesEnergy supplyAdaptation potentialBiomedical effects
Finding an algorithm for determining blood pressure (BP) along the pulse wave contour (PW) is the most difficult task after solving the problem of obtaining the most undistorted PW signal.
Algorithm for determining blood pressure (BP)The contour of PWArterial tonometerSpline base of PW reference standard curve patternsMedical accuracy of blood pressure determination
Right ventricular echocardiographic predictors of functional capacity in patients with heart failure with reduced ejection fraction
Patients with chronic heart failure (CHF) experience marked reduction in their exercise capacity which has detrimental effects on their activities of daily living, health- related quality of life (HRQoL), and ultimately their hospital admission rate and mortality.
Heart failureFunctional capacityEchocardiography