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Systematic design of optimized pulse shape for transthoracic defibrillation

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In the study conducted by us previously, it was found that not only the energy of the discharge, but also the amplitude of current, the pulse duration and its shape have their significant influence on the efficacy of defibrillation. Until now, no systematic approach to the comparison of the pulse shapes effectiveness has been available. An identification of the optimal pulse parameters for defibrillation has not only theoretical aspects but also engineering details in the design implementation. In order to conduct a complete pulse optimization, required is a multidisciplinary approach to determining boundary values and searching for further ways to improve the efficiency of electropulse therapy. An understanding of the relationship between the biphasic pulse parameters and the criteria for healthcare quality can make it possible to increase the survival rate of patients with ventricular fibrillation and ventricular tachycardia. The implementation of the current stabilization system in the defibrillator allows realizing an individual selection of the pulse energy defibrillation.


Nikolay N. Chernov, Oksana I. Korotkova, Aleksandr A. Bezverkhii. Systematic design of optimized pulse shape for transthoracic defibrillation. Cardiometry; Issue 17; November 2020; p.34-38; DOI: 10.12710/cardiometry.2020.17.3438; Available from:


Transthoracic defibrillation,  Biphasic pulse,  Current stabilization,  Cardiomyocytes repolarization,  Ventricular fibrillation
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