No.24 November 2022

Fundamental research studies in cardiology and oncology

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Essay

Professor Yuriy N. Bordyushkov

Professor Yuriy N. Bordyushkov, MD, Doctor of Medical Sciences, representative of the excellent cohort of the Rostov School of Oncologists, who holds the lead in research in the field of adaptation and increase of nonspecific antitumor resistance by a human organism, and, in general, who has pioneered in identifying the growth points in fundamental oncology.

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Original research

Contact effects by mitochondria: biological destruction of cultivated B16 – F10 melanoma cells

In recent years therapeutic effects produced by mitochondria, transplanted to pathogenic regions in an organism, which demonstrate their high migration activity and tropicity with respect to filling of energetic vacuum, have been inspiring a renewed interest in the scientific community.
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Original research

Properties of melanoma mitochondria to form tumor nodules in the body of experimental animals

The aim hereof is to develop a method for revealing the properties of mitochondria isolated from melanoma of the skin to form melanoma tumor nodules in the body of mice in parenteral transplantation of melanoma mitochondria.
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Report

Functional state of the cardiovascular system in women during pregnancy

The article presents the results of studying the effect of pregnancy on the functional state of the cardiovascular system in women.
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Original research

Transcatheter closure of secundum atrial septal defects in Egyptian centers: immediate and short-term outcomes

Considered is the Atrial Septal Defect (ASD), with secundum ASDs being the most frequent. As known, in comparison to surgical approach, device closure of secundum ASD is less invasive, has few post-procedural complications, reduced anaesthesia risks, and has early hospital discharge.
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Original research

Antithrombotic therapy of pregnant women suffering from certain congenital cardiopathologies

The paper discusses the features of antithrombotic therapy of pregnant women suffering from congenital cardiopathologies.
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Editorial

The all-russian scientific and practical conference with international participation “Fundamental research: stopper or driver in modern oncology?”

The Conference is dedicated to the 45th anniversary of the scientific discovery “Pattern of Development of Qualitatively Differing General Unspecific Adaptation Reactions of the Organism” made by Garkavi L.Kh., Ukolova E. B. and Kvakina E.B. and 115th anniversary of the birth of Professor Ukolova M.A., the founder of the experimental department at the National Medical Research Center for Oncology at the Ministry of Health of Russia.

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Original research

Mitochondria stimulate liver regeneration in rats

Regenerative medicine is a vital area that advances methods addressing the process of liver regeneration. The liver has the unique ability to return to standard size within a short period of time after its injury or partial hepatectomy.
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Original research

Mathematical modeling of flows in blood vessels of complex shape

A study of the structure and topography of the cerebral arterial bed of 156 virtually healthy individuals verified 17 variants of the arterial circle of the great brain, most of which are shown in actual photographs.
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Case report

Cushing Reflex Variant: A case report

In our case, we report a 67-year-old male admitted with lower limb ischemia for angiography under vascular surgery.
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Review

Review and classification of diagnostic methods of the cardiovascular system

Cardiovascular disease ranks first among the causes of morbidity and mortality in the elderly.
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Original research

The state of the cardiovascular system in female students after use of different doses of caffeine

Our article is devoted to the study of the state of the cardiovascular system in female students after the use of different doses of caffeine. Drinking 200 mg of coffee leads to a significant increase in heart rhythm and diastolic blood pressure in girls.
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Original research

Contribution of mitochondrial therapy to processes of regeneration and selforganization of the cell system of the resected liver in rats

Studies of the processes of the regeneration in the liver are not new, but however the development of the technologies of bio-therapy is capable of shifting the conventional approaches to the regeneration of the lost tissues.
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Original research

Mechanisms of tumor-associated cardiac muscle damage under different variants of melanoma growth

In case of the presence of a malignant process in an organism, the heart is subjected to an additional loading due to a unique combination of the external factors that is determined by the tumor biology and potentially cardiotoxic treatment actions and effects.
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Original research

Cardiometric assessment of the subjective significance of personal strategicgoals as components of the image of the desired future

The article presents some experimental results demonstrating the suitability of using the psycho-physiological reactions recorded with the Cardiocode device and the Barrier-14 polygraph to specially selected visual stimuli in order to assess the degree of authenticity of vital goals chosen by a person as key benchmarks in the implementation of the desired future.
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Review

Survival and Fracture rates of One-Piece Zirconia Implants: A Systematic review

The implementation of endosseous showed expected outcomes related to survival and successful oral management.
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Original research

Possible manifestations of cognitive impairment in children suffering from pancreatic dysfunction

The article investigates possible manifestations of cognitive impairment in children suffering from pancreatic dysfunction.
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Case report

Combination of type I diabetes mellitus and diabetes associated with GCK gene mutation: features of the clinical course in puberty

This article discusses a clinical case of the manifestation of MODY2 diabetes, which complicated the course of type I diabetes mellitus in a patient of puberty.
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