Novel formula to measure mean pulmonary artery pressure

Abstract

Mean Pulmonary Arterial Pressure (MPAP) is an important parameter in evaluation of patients with pulmonary hypertension. The aim of this study is to correlate a new formula using non-invasive blood pressure and Bernoulli’s right ventricle systolic pressure (RVSP) with invasive method. To archive the objectives, we enrolled 143 patients with suspected pulmonary hypertension from January 2015 till January 2016; all patients underwent right heart catheter evaluation and simultaneously RVSP by transthoracic echocardiography and non-invasive blood pressure to calculate MPAP by the formula MPAP = Pulse Pressure / (Mean Arterial Pressure/RVSP); and the results were compared using the Pearson’s simple-linear correlation method. We found a significant association between invasive and equation results with a Pearson’s correlation of 0,872 with a confidence interval from 0,795 to 0,921; sensitivity was 1,538% with a 95% confidence of interval (CI) from 0,038% to 8,276%, and Specificity was 100% with 95% CI from 94,48% to 100%. Our results suggest that the new formula have a good correlation estimating MPAP compared with invasive right heart catheterization method.

Imprint

Francisco Jose Chacon-Lozsan, Elizaveta O. Lebedeva, Juan Sebastian Peinado-Acevedo. Novel formula to measure mean pulmonary artery pressure. Cardiometry; Issue 9; November 2016; p. 74-76; DOI:10.12710/cardiometry.2016.9.7476 Available from: http://www.cardiometry.net/issues/no9-november-2016/pulmonary-artery-pressure