Evaluations of bone turnover in a sample of Iraqi postmenopausal hypertensive obese women

Abstract

Background: Hypertension and osteoporosis are worldwide diseases with high prevalence; the study was done to estimate the correlation between hypertension and bone turnover in a sample of Iraqi postmenopausal women with hypertension and obesity. Materials and Methods: A cross-sectional study was done on 99 hypertensive obese postmenopausal Iraqi women (65 hypertensive obese and 34 normotensive non-obese). The serum calcium (Ca), phosphorus (Pi), and alkaline phosphatase (ALP) levels were measured as a representative of bone markers. Results: The results demonstrated that serum alkaline phosphatase is significantly elevated in the case group compared to the controls. No significant changes were observed in the levels of Ca and Pi in the patient group, while a significant increase in alkaline phosphatase was observed. Conclusions: The study shows that the changes in the bone markers in the patient group are important risk factors and contribute to osteoporosis, and it declares the effect of hypertension on bone turnover markers in Iraqi postmenopausal women with hypertension and obesity.

Imprint

Isam Noori Salman, Noor Ulhuda G. Mohammed, Safaa Ehssan Atta, Baydaa Ahmed Abed, Hussein Hatam omran. Evaluations of bone turnover in a sample of Iraqi postmenopausal hypertensive obese women. Cardiometry; Issue 32; August 2024; p.55-59; DOI: 10.18137/cardiometry.2024.32.5559; Available from: https://www.cardiometry.net/issues/no32-august-2024/evaluations-bone-turnover-sample