Prevalence of pan drug-resistant, extensively drug-resistant, and detection of multiple antibiotic resistance in uncommon bacterial isolates in Al-Al Zahraa teaching hospital for Maternity and children in Najaf/Iraq

Abstract

Objectives: There are numerous opportunistic bacterial species that are unusual and rarely found in laboratory samples, most are challenging to routinely identify, some of them even being documented very little in clinical samples. Also, the role of these species in the coordinates of the disease is no less average and important than the common bacterial species. Materials and Methods: A retrospective study was done among the patients those were admitted to Al Zahraa Teaching hospital for Maternity and Children in Najaf between June to October 2022. All patients were incorporated into our study. Bacterial isolates were identified using the conventional morphological, and VITEK 2 method for identifying rare and unusual isolates as well as measurement of Minimum Inhibitory Concentration. 52 Uncommon bacterial isolates were found in a variety of lesions. The profiles of antimicrobial susceptibility for the different isolates were examined. Uncommon bacterial isolates were further categorized as multiple-drug-resistant (MDR), extremely drug-resistant (XDR), and pan-drug-resistant (PDR) based on standardized worldwide standards. Results: Fifty-two uncommon bacterial isolates collected from individuals who were affected with different infections. Of these 37(71.2%) isolates found to be gram negative bacteria and 15(28.8%) isolates found to be gram-positive bacteria. All isolates were subjected to calculation of the (MAR) multiple antibiotic resistance index that showed large values > 0.2 rankings (0.21-0.94) based on the highest MAR index (1) excluded E. vulneris (0.12). Conclusions: Antimicrobial resistance is a growing issue, and how to manage it is of concern. The current study reveals the concerning levels of antibiotic resistance among uncommon bacterial species.

Imprint

Karrar Abdil Aziz Ali Beg, Asmaa Hassan Khudair, Dafer Mahammad Hussein Etaij, Ahmed Abdullah Mezher, Ammar Abdul Aziz Ali beg. Prevalence of pan drug-resistant, extensively drug-resistant, and detection of multiple antibiotic resistance in uncommon bacterial isolates in Al-Al Zahraa teaching hospital for Maternity and children in Najaf/Iraq. Cardiometry; Issue 30; February 2024; p.41-49; DOI: 10.18137/cardiometry.2024.30.4149; Available from: https://www.cardiometry.net/issues/no30-february-2024/prevalence-pan-drug-resistant-extensively