Oxidative stress and one carbon metabolism in prostate neoplasm

Shweta Kumari¹, Juhi Aggarwal¹, Urvashi Midha¹, Jyoti Batra¹, Nikkita Gupta¹

¹ Santosh Medical College and Hospital, Santosh deemed to be University, Ghaziabad, Uttar Pradesh -201009

Abstract

Carcinoma of the prostate is the most common malignant tumour in men over the age of 65 years with peak age of incidence between 70 and 74 years. Oxidative stress and one carbon metabolism are important contributary factors in etiopathogenesis in Prostate Neoplasm. Significant increase in oxidative stress and serum homocysteine level and no difference of serum vitamin B12 was found in BPH and prostate cancer cases compared to control group. Following review compare level of Oxidative Stress Marker and One Carbon Metabolism markers between Prostate neoplasm patients and control Group. Antioxidant drugs may play a role in influencing outcome in these patients. However, randomized trials are required to investigate.

Imprint

Shweta Kumari, Juhi Aggarwal, Urvashi Midha, Jyoti Batra, Nikkita Gupta. Oxidative stress and one carbon metabolism in prostate neoplasm . Cardiometry; Issue 25; December 2022; p.1202-1204; DOI: 10.18137/cardiometry.2022.25.12021204; Available from: https://www.cardiometry.net/issues/no25-december-2022/oxidative-stress-one-carbon

Keywords

Prostate carcinoma, Ooxidative stress, Homocysteine, Folate

Download PDF

Current issue