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Multifactorial utility of vitamins in treatment of COVID–19


The pathogenesis of the SARS-CoV-2 virus responsible for COVID-19 disease is ever unravelling. Researchers are continuously generating evidence regarding the mechanism of the infection and its complications. There is also an attempt to understand the role of various biomolecules in preventing or treating COVID-19 disease and its complications. Trials show that Vitamin D decreases the rate of admission in ICU. Vitamin C is known to exert the positive influence in decreasing the intensity of viral infections and severe sepsis. Vitamin B12 plays a pivotal role in gut microbiome management. Dietary supplementation of micronutrients with defined roles in immune function can streamline the balance of the body's immune reaction, lessening the incidence of infections and ICU hospital stay.The focus of this review is to apply our modern knowledge of vitamin D, B12 and C as micronutrients & facilitator of immune competence. We suggest that vitamins D, B12 and C may serve as attenuators to COVID-19 symptoms. Large randomized trials are required to confirm this hypothesis.


Juhi Aggarwal, Suruchi Mathur, Jyoti Batra. Multifactorial utility of vitamins in treatment of COVID – 19. Cardiometry; Issue 25; December 2022; p.1197-1201; DOI: 10.18137/cardiometry.2022.25.11971201; Available from:


Vitamin D,  Vitamin C,  Vitamin B 12 ,  COVID-19
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