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Original research

To assess the level of serum uric acid in first trimester to predict gestational diabetes mellitus

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Abstract

The present study aims to assess the uric acid levels in first trimester to predict the gestational diabetic mellitus. Materials And Methods: The quantitative approach with prospective cohort study was conducted in the host institution of Saveetha Medical College And Hospitals. A total of 60 study participants were recruited using purposive sampling technique based on the inclusion criteria, the demographic and clinical data was collected by using a self-structured questionnaire and the levels of serum uric acid was estimated during 0-12 weeks and the study participants were followed till 24- 28 weeks of gestation , and the levels of Oral Glucose Tolerance Test ( Oral GTT) were estimated during 24- 28 weeks of gestation. Results: The outcome results identified that, among our study participants during 0-12 weeks of gestation, 10% had uric acid level less than normal,73.3% had normal uric acid level, 16.7% had uric acid level more than normal and after a follow up till 24- 28 weeks Oral Glucose Tolerance Test (Oral GTT) and the results identified that, among our study participants 86.67% were not at the risk of developing GDM during pregnancy and 13.33% had the risk of developing GDM during pregnancy. Conclusion: This study demonstrates a positive association between increased first trimester uric acid and GDM.

Imprint

Padmapriya D., Jonah Abraham R., Logambal K.. To assess the level of serum uric acid in first trimester to predict gestational diabetes mellitus. Cardiometry; Issue 25; December 2022; p.213-219; DOI: 10.18137/cardiometry.2022.25.213219; Available from: https://www.cardiometry.net/issues/no25-december-2022/assess-level-serum-uric-acid

Keywords

Gestational diabetes mellitus,  Oral glucose tolerance test,  Serum uric acid
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