Correlation between neutrophil to lymphocyte ratio (NLR) and red cell distribution width to platelet ratio with ST segment resolution and 2 month complications in patients with acute myocardial infarction undergoing primary coronary intervention

Abstract

Acute myocardial infarction causes a great number of mortality and morbidity each year. Risk assessment and prognosis is one of the initial steps in approaching a patient with acute myocardial infarction. Neutrophil to lymphocyte ratio (NLR) and red cell distribution width to platelet ratio (RPR) are two indices that have been studied recently and their prognostic and risk assessment role is reported in various studies. In this study we aimed to investigate the relationship between NLR and RPR with ST segment resolution (STR) in patients with acute myocardial infarction.

Materials and methods

This is a cohort study with 2 months of follow up and a total of 211 patients with acute myocardial infarction were enrolled in the study. An electrocardiogram and venous blood sample was taken from all included patient and the results were recorded in a questionnaire. All patients underwent primary coronary intervention and another electrocardiogram was retrieved within 90 minute after primary angioplasty. Data was analyzed using SPSS 16.

Results

Our results showed that the mean age of participants was 61.15±12.68 years. Among 211 patients, 181 (85.8%) were male and 30 (14.2%) were female. The mean RPR, NLR and SRT in the studied patients was 1.01±0.21, 4.07±3.31 and 0.418±0.32 respectively. There was a significant correlation between NLR and RPR with STR along with two month complications in studied patients.

Conclusion

According to our results, NLR and RPR can be used for risk assessment and prognosis and short term complications of myocardial infarction in patients undergoing primary coronary intervention.

Imprint

Hamidreza Varastehravan, Aryan Naghedi, Azam Yalameh Aliabadi, Seyedeh Mahdieh Namayandeh, Pardis Rezaei Shirinabadi. Correlation between neutrophil to lymphocyte ratio (NLR) and red cell distribution width to platelet ratio (RPR) with ST segment resolution (STR) and 2 month complications in patients with acute myocardial infarction undergoing primary coronary intervention. Cardiometry; Issue 15; November 2019; p.49-55; DOI: 10.12710/cardiometry.2019.15.4955; Available from: http://www.cardiometry.net/issues/no15-november-2019/acute-myocardial-infarction