Comparative study of glycemic control and treatment satisfaction for patients with type 1 diabetes on sensor augmented insulin pump, insulin pump and multiple daily insulin injection: cross sectional study

Abstract

BACKGROUND:All patients with T1DM are on life-long insulin injection . However, since last decades with evolving diabetes technology ,there is a paucity of research on glycemic and self satisfaction effectiveness of new insulin pump and CGM devices in Saudi Arabia population whom they have different lifestyle and race. PATIENTS AND METHODS:A cross-sectional study was conducted at King Abdulaziz Medical City Endocrine Center in Riyadh, Saudi Arabia. The study focused on a sample of patients with type 1 diabetes aged 14 years and above using either a sensor-augmented insulin pump (Medtronic MiniMed 640G, 740G) , insulin pump without a sensor (Medtronic Paradigm VEO 754), or multiple daily insulin injections for at least 6 months. RESULTS:196 patients with type 1 diabetes were included, with the majority (76.5%) being females. Their age ranged between 14 and 55 years. More than half of the patients (52.5%) were treated with multiple daily insulin injections. In comparison, 25% and 8.2% were treated with insulin pumps with sensor G640/newer and insulin pumps without sensors, respectively. Multiple linear regression indicated that patients treated with insulin pumps with sensors had lower HbA1c levels than those who received multiple daily insulin injections. Additionally, patients treated with insulin pumps with sensors had significantly higher patient satisfaction scores than those treated with multiple daily insulin injections, indicating that the frequency of educator visits was responsible for approximately 20% variability of the patient's satisfaction score (r-square = 0.202). CONCLUSIONS:Using insulin pumps with sensors to treat patients with type 1 diabetes mellitus is superior to using multiple daily insulin injections in glycemic control, frequency of hyperglycemia,and patient satisfaction.

Imprint

Ali A. Alshahrani MD,MBBS, Fajr S. Almutairi BSN. Comparative study of glycemic control and treatment satisfaction for patients with type 1 diabetes on sensor augmented insulin pump, insulin pump and multiple daily insulin injection: cross sectional study. Cardiometry; Issue 30; February 2024; p.62-72; DOI: 10.18137/cardiometry.2024.30.6272; Available from: https://www.cardiometry.net/issues/no30-february-2024/comparative-study-glycemic-control-treatment